University of Pittsburgh Department of Cell Biology

Events

  • Tuesday, December 7, 2021 11:00 am
    Virtual
    Salt intake, glucocorticoids and hypertension
    Matthew Bailey, PhD, Personal Chair of Renal Physiology, Centre for Cardiovascular Science, The University of Edinburgh
  • Tuesday, January 18, 2022 11:00 am
    5th Floor Boardroom, Eye & Ear Institute
    Structural, mechanistic, and allosteric determinants of mTOR Complex 2 (mTORC2) activation of Akt
    Martin Taylor, MD, PhD, Massachusetts General Hospital & Harvard Medical School, Department of Pathology

New Publications

  • New Publication!
    Alexander Sorkin, Ph.D.
    Surve S, Watkins SC, Sorkin A. EGFR-RAS-MAPK signaling is confined to the plasma membrane and associated endorecycling protrusions. J Cell Biol. 2021 Nov 1;220(11):e202107103. doi: 10.1083/jcb.202107103. Epub 2021 Sep 13. PMID: 34515735; PMCID: PMC8563293.
  • New Publication!
    Yi Shi, Ph.D.
    A resource of high-quality and versatile nanobodies for drug delivery. Zhuolun Shen, Yufei Xiang, Sandra Vergara, Apeng Chen, Zhengyun Xiao, Ulises Santiago, Changzhong Jin, Zhe Sang, Jiadi Luo, Kong Chen, Dina Schneidman-Duhovny, Carlos Camacho, Guillermo Calero, Baoli Hu, Yi Shi. iScience. 2021. 103014. ISSN 2589-0042. https://doi.org/10.1016/j.isci.2021.103014.
  • New Publication!
    Alexander Sorkin, Ph.D.
    von Zastrow, M., and Sorkin, A. Mechanisms for Regulating and Organizing Receptor Signaling by Endocytosis. Ann. Rev. Biochemistry (2021) 90:5.1–5.29. https://doi.org/10.1146/annurev-biochem-081820-092427
  • New Publication!
    Yi Shi, Ph.D.
    Sun, D., Sang, Z., Kim, Y.J. et al. Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes. Nat Commun 12, 4676 (2021). https://doi.org/10.1038/s41467-021-24963-3.
  • New Publication!
    Alexander Sorkin, Ph.D.
    Perez Verdaguer, M., Zhang, T., Paulo, J. A., Gygi, S., Watkins, S. C., Sakurai, H., & Sorkin, A. (2021). Mechanism of p38 MAPK-induced EGFR endocytosis and its crosstalk with ligand-induced pathways. J. Cell Biol., 220(7), e202102005.
  • New Publication!
    Yi Shi, Ph.D.
    Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses. Sham Nambulli, Yufei Xiang, Natasha L. Tilston-Lunel, Linda J. Rennick, Zhe Sang, William B. Klimstra, Douglas S. Reed, Nicholas A. Crossland, Yi Shi, W. Paul Duprex. Science Advances. 2021.Vol. 7, no. 22, eabh0319. DOI: 10.1126/sciadv.abh0319.
  • New Publication!
    Adam Kwiatkowski, Ph.D.
    Distinct intramolecular interactions regulate autoinhibition of vinculin binding in αT-catenin and αE-catenin. Jonathon A. Heier, Sabine Pokutta, Ian W. Dale, Sun Kyung Kim, Andrew P. Hinck, William I. Weis, Adam V. Kwiatkowski. Journal of Biological Chemistry. 2021. 100582. ISSN 0021-9258.
  • New Publication!
    Yang Hong, Ph.D.
    Electrostatic plasma membrane targeting contributes to Dlg function in cell polarity and tumorigenesis. Juan Lu, Wei Dong, Yan Tao, Yang Hong. Development 2021: dev.196956 doi: 10.1242/dev.196956.
  • New Publication!
    Yi Shi, Ph.D.
    Integrative proteomics identifies thousands of distinct, multi-epitope, and high-affinity nanobodies. Yufei Xiang, Zhe Sang, Lirane Bitton, Jianquan Xu, Yang Liu, Dina Schneidman-Duhovny, Yi Shi. Cell Systems. 2021. ISSN 2405-4712. https://doi.org/10.1016/j.cels.2021.01.003.
  • New Publication!
    Michael B. Butterworth, Ph.D.
    Non-coding RNAs and the mineralocorticoid receptor in the kidney. Butterworth MB. (2021). Mol Cell Endocrinol. 521:111115. PMID: 33301840