1. He M., Zhou Z., Wu G., Chen Q. and Wan Y. 2017. Ubiquitinase protein ligase and deubiquitinase in tumor metastasis and therapeutics. Pharmacology & Therapeutics (in press)
  2. Zhihua Liu, Honghong Zhou, Yong-Shuo Liu, Rui Zhu, Fang Ding, Yong Wan, and Yi Li. 2017. FBXO32 suppresses breast cancer tumorigenesis through targeting KLF4 to proteasomal degradation. Oncogene (in press)
  3. Zhou Z, Shrivastava I, Lou A, He M, Huang Y, Liu Z, Bahar I and Wan Y. 2017. Novel insight into USP11-XIAP axis in malignant tumor transformation. EBioMedicine (in press).
  4. He M, Zhou Z, Shah AA, Tao J, Zou H, Chen Q, and Wan Y. 2016. The emerging role of deubiquitinating enzymes in genomic integrity, diseases, and therapeutics. Cell and Bioscience. (in press)
  5. Zhou Z, He M, Shah AA, and Wan Y. 2016. Insight into APC/C: from cellular function to diseases and therapeutics. Cell Div. Jul 13; 11:9 PMID: 27418942
  6. He M, Zhou Z, Shah AA, Hong Y, Chen Q and Wan Y. 2016. New insights into posttranslational modifications of Hippo pathway in carcinogenesis and therapeutics. Cell Div. Mar 31;11:4. PMID: 27042197
  7. Hu. D*., Gur M*., Zhou Z., Fujita N., Hung M-Q, Lan L., Bahar I. and Wan Y. (2015). Interplay between KLF4 by PRMT5 in genome stability and carcinogenesis. Nat Commun. Sep 30;6:8419. PMID: 26420673
  8. He H, Li S, Hong Y, Zou H, Chen H, Ding F, Wan Y, Liu Z. 2015. Krüppel-like Factor 4 Promotes Esophageal Squamous Cell Carcinoma Differentiation by Up-regulating Keratin 13 Expression. J Biol Chem. 22;290(21):13567-77. PMID: 25851906
  9. Zhou Z., Chao J., Zhang L., Takeo F., Kim H., Huang Y., Liu Z. and Wan Y. (2013) Regulation of Rad17 turnover unveils an impact of Rad17-APC cascade in breast carcinogenesis and treatment. J Biol Chem 288(25):18134-45. PMID:23637229
  10. Vasilatos S.N., Katz T.A., Oesterreich S, Wan Y, Davidson N.E. and Huang Y. 2013. Crosstalk between LSD1 and HDACs Mediates Anti-tumor Efficacy of HDAC Inhibitors in Human Breast Cancer Cells. Carcinogenesis (Epub in ahead of print) PMID: 23354309
  11. Gamper A., Kim J., Qiao X. Rathmell K. and Wan Y. 2012. Proteolytic regulation of Krüppel-like Factor 4 (KLF4) by VHL E3 ligase in breast carcinogenesis. Mol Cell. (Epub in ahead of print) PMID: 22284679
  12. Hu D., Zhou Z., Davidson N.E., Huang Y. and Wan Y. (2012). Novel insight into KLF4 proteolytic regulation in estrogen signaling and breast carcinogenesis. J Biol Chem. 20: 287(17): 13584-97 PMID:22389506
  13. Liu YN, Abou-Kheir W, Yin JJ, Fang L, Hynes P, Casey O, Hu D, Wan Y, Seng V, Sheppard-Tillman H, Martin P, Kelly K. (2011) Critical and reciprocal regulation of KLF4 and SLUG in TGF-beta-initiated prostate cancer EMT. Mol Cell Biol. Dec 27. Epub ahead of print. PMID: 22203039
  14. Hu D., Qiao X., Wu, G., Kim H and Wan Y. 2011. The role of anaphase-promoting complex in developmental control. Seminars in Cell & Develop Biol. (Epub ahead of print) PMID: 21497201
  15. Liu W., Zong W., Wu G., Liu X., and Wan Y. (2011). Turnover of BRCA1 Involves in Radiation-Induced Apoptosis. PLoS ONE Dec 31;5(12):e14484 PMID: 21217819
  16. Zhang L., Fujita T., Wu G., Xiao X. and Wan Y. (2011). Phosphorylation of Anaphase-Promoting Complex Is Involved in TGF-beta Signaling Pathway. J Biol Chem. Jan 5. (Epub ahead of print) PMID: 21209074
  17. Hu D., Liu W., Wu. G and Wan Y. (2011). Nuclear translocation of Skp2 facilitates its destruction in response to TGF-beta signaling. Cell Cycle Jan 15;10(2). (Epub ahead of print) PMID: 21212736
  18. Hu D. and Wan Y. (2011). Regulation of Krüppel-like Factor 4 (KLF4) by APC pathway in TGF-beta signaling. J Biol Chem Dec 22. (Epub ahead of print) PMID: 21177849
  19. Zhang L., Park C-H, Wu J., Kim H., Liu W., Fujita T., Balasubramani M., Schreiber E.M., Wang X-F and Wan Y. (2010) Proteolysis of Rad17 by Cdh1/APC involves in checkpoint termination and recovery from genotoxic stress. EMBO J. 29(10): 1726-37. PMID: 20424596
  20. Qiao X., Zhang L. Gamper A. Fujita T. and Wan Y. (2010) Cdh1/APC: from cell cycle, genomic integrity to carcinogenesis. Cell Cycle Oct 1;9(19):3904-12. (Epub in ahead of print). PMID: 20935501
  21. Fujita T., Liu W., Doihara H. and Wan Y. (2009) In vivo dissection of Cdh1/APC in breast carcinogenesis. Int J Cancer. 125(4): 826-36. PMID: 19350629
  22. Fujita T., Epperly M.W., Zou H., Gollin S.M., Greenberger J.S., and Wan Y. (2008) Regulation of the Anaphase promoting complex-separase cascade by transforming growth factor-beta modulates mitotic progression in bone marrow stromal cells. Mol Biol Cell. 19: 5446-5455 PMID:18843049
  23. Fujita T. Doihara H., Liu W. and Wan Y. (2008) Dissection of the APCCdh1-Skp2 cascade in breast cancer. Clin Cancer Res 14 (7): 1966-1975 PMID:18381934
  24. Liu W., Fujita T., Li W., Yang Q., and Wan Y. ( 2008) Proteolysis of CDH1 enhances susceptibility to UV radiation induced apoptosis. Carcinogenesis 29 (2): 263-72. PMID:18174259
  25. Fujita T. Liu W., Hiroyoshi D. and Wan Y.. (2008) Regulation of Skp2-p27 axis by the Cdh1/anaphase promoting complex pathway in colorectal tumorigenesis. Am J. Pathol. Vol 173, No.1, 217-28. PMID:18535175
  26. Liu W., Wu G., Lobur D., Li W., and Wan Y. (2007) Cdh1-APC targets Skp2 for destruction in TGF-beta Induced growth inhibition. Mol Cell Biol. Vol.27 (8):2967-79 PMID: 17283060
  27. Wu G., Glickstein S., Liu W, Fujita T., Li W., Yang Q., Duvoisin R., and Wan Y. (2007) The APC coordinates the initiation of lens differentiation. . Mol Biol Cell. Vol 18 (3):1018-29. PMID:17215516
  28. Li W., Wu G., and Wan Y. (2007) The dual effects of Cdh1 in myogenesis. FASEB J. 21(13): 3606-17. PMID:17601983
  29. Wei W*, Ayad NG*, Wan Y, Zhang GJ, Kirschner MW, Kaelin WG Jr. 2004. Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex. Nature 428:194-8. PMID:15014503
  30. Macdonald M., Wan Y., Wang W., Roberts B., Cheung T., Erickson R., Kirschner M. W. and Liu X. 2004. Cdc34 is required for cell cycle dependent degradation of c-Ski proto-oncoprotein. Oncogene 23(33): 5643-53 PMID:15122324
  31. Knuesel MP, Wan Y., Xia Z, Holinger EP, Lowe N, Wang W, Liu X. 2003. Identification of novel protein-protein interactions using a versatile mammalian TAP expression system. Mol Cell Proteomics (11): 1225-33 PMID:12963786
  32. Wan Y., Liu X. and Kirschner W. M. 2001. The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction. Molecular Cell 8(5): 1027-1039. PMID:11741538
  33. Wan Y. and Kirschner W. M. 2001. Identification of multiple CDH1 homologues in vertebrates conferring different substrate specificities. Proc. Natl. Acad. Sci. USA 98: 13066-13071. PMID:11687641
  34. Jiang Y., Ma W., Wan Y., Kozasa T., Hassatli T., and Huang X-Y. 1998. G12 directly stimulates a tyrosine kinase and a Ras-Gap through conserved PH-BM domain. Nature 395: 808-813. PMID:9796816
  35. Wan Y. and Huang X-Y. 1998. Analysis of the Gs/mitogen-activated protein kinase pathway in mutant S49 cells. J. Biol. Chem. 273: 14533-14537. PMID:9603967
  36. Wan Y., Bence K., Hata A., Kurosaki T. Veillette A., and Huang X-Y. 1997. Genetic evidence for a tyrosine kinase cascade preceding the mitogen-activated protein kinase cascade in vertebrate G-protein signaling. J. Biol. Chem. 272: 17209-17215. PMID:9202044
  37. Wan Y., Kurosaki T., and Huang X-Y. 1996. Tyrosine kinases in activation of the MAP kinase cascade by G-protein-couple receptors. Nature 380: 541-544. PMID:8606776
  38. Langhans-Rajasekaran S., Wan Y., and Huang X-Y. 1995. Activation of Tsk and Btk tyrosine kinases by G protein beta-gamma subunits. Proc. Natl. Acad. Sci. USA . 92: 8601-8605. PMID:7567982