- He M., Zhou Z., Wu G., Chen Q. and Wan Y. 2017. Ubiquitinase protein ligase and deubiquitinase in tumor metastasis and therapeutics. Pharmacology & Therapeutics (in press)
- Zhihua Liu, Honghong Zhou, Yong-Shuo Liu, Rui Zhu, Fang Ding, Yong Wan, and Yi Li. 2017. FBXO32 suppresses breast cancer tumorigenesis through targeting KLF4 to proteasomal degradation. Oncogene (in press)
- Zhou Z, Shrivastava I, Lou A, He M, Huang Y, Liu Z, Bahar I and Wan Y. 2017. Novel insight into USP11-XIAP axis in malignant tumor transformation. EBioMedicine (in press).
- He M, Zhou Z, Shah AA, Tao J, Zou H, Chen Q, and Wan Y. 2016. The emerging role of deubiquitinating enzymes in genomic integrity, diseases, and therapeutics. Cell and Bioscience. (in press)
- Zhou Z, He M, Shah AA, and Wan Y. 2016. Insight into APC/C: from cellular function to diseases and therapeutics. Cell Div. Jul 13; 11:9 PMID: 27418942
- He M, Zhou Z, Shah AA, Hong Y, Chen Q and Wan Y. 2016. New insights into posttranslational modifications of Hippo pathway in carcinogenesis and therapeutics. Cell Div. Mar 31;11:4. PMID: 27042197
- Hu. D*., Gur M*., Zhou Z., Fujita N., Hung M-Q, Lan L., Bahar I. and Wan Y. (2015). Interplay between KLF4 by PRMT5 in genome stability and carcinogenesis. Nat Commun. Sep 30;6:8419. PMID: 26420673
- He H, Li S, Hong Y, Zou H, Chen H, Ding F, Wan Y, Liu Z. 2015. Krüppel-like Factor 4 Promotes Esophageal Squamous Cell Carcinoma Differentiation by Up-regulating Keratin 13 Expression. J Biol Chem. 22;290(21):13567-77. PMID: 25851906
- Zhou Z., Chao J., Zhang L., Takeo F., Kim H., Huang Y., Liu Z. and Wan Y. (2013) Regulation of Rad17 turnover unveils an impact of Rad17-APC cascade in breast carcinogenesis and treatment. J Biol Chem 288(25):18134-45. PMID:23637229
- Vasilatos S.N., Katz T.A., Oesterreich S, Wan Y, Davidson N.E. and Huang Y. 2013. Crosstalk between LSD1 and HDACs Mediates Anti-tumor Efficacy of HDAC Inhibitors in Human Breast Cancer Cells. Carcinogenesis (Epub in ahead of print) PMID: 23354309
- Gamper A., Kim J., Qiao X. Rathmell K. and Wan Y. 2012. Proteolytic regulation of Krüppel-like Factor 4 (KLF4) by VHL E3 ligase in breast carcinogenesis. Mol Cell. (Epub in ahead of print) PMID: 22284679
- Hu D., Zhou Z., Davidson N.E., Huang Y. and Wan Y. (2012). Novel insight into KLF4 proteolytic regulation in estrogen signaling and breast carcinogenesis. J Biol Chem. 20: 287(17): 13584-97 PMID:22389506
- Liu YN, Abou-Kheir W, Yin JJ, Fang L, Hynes P, Casey O, Hu D, Wan Y, Seng V, Sheppard-Tillman H, Martin P, Kelly K. (2011) Critical and reciprocal regulation of KLF4 and SLUG in TGF-beta-initiated prostate cancer EMT. Mol Cell Biol. Dec 27. Epub ahead of print. PMID: 22203039
- Hu D., Qiao X., Wu, G., Kim H and Wan Y. 2011. The role of anaphase-promoting complex in developmental control. Seminars in Cell & Develop Biol. (Epub ahead of print) PMID: 21497201
- Liu W., Zong W., Wu G., Liu X., and Wan Y. (2011). Turnover of BRCA1 Involves in Radiation-Induced Apoptosis. PLoS ONE Dec 31;5(12):e14484 PMID: 21217819
- Zhang L., Fujita T., Wu G., Xiao X. and Wan Y. (2011). Phosphorylation of Anaphase-Promoting Complex Is Involved in TGF-beta Signaling Pathway. J Biol Chem. Jan 5. (Epub ahead of print) PMID: 21209074
- Hu D., Liu W., Wu. G and Wan Y. (2011). Nuclear translocation of Skp2 facilitates its destruction in response to TGF-beta signaling. Cell Cycle Jan 15;10(2). (Epub ahead of print) PMID: 21212736
- Hu D. and Wan Y. (2011). Regulation of Krüppel-like Factor 4 (KLF4) by APC pathway in TGF-beta signaling. J Biol Chem Dec 22. (Epub ahead of print) PMID: 21177849
- Zhang L., Park C-H, Wu J., Kim H., Liu W., Fujita T., Balasubramani M., Schreiber E.M., Wang X-F and Wan Y. (2010) Proteolysis of Rad17 by Cdh1/APC involves in checkpoint termination and recovery from genotoxic stress. EMBO J. 29(10): 1726-37. PMID: 20424596
- Qiao X., Zhang L. Gamper A. Fujita T. and Wan Y. (2010) Cdh1/APC: from cell cycle, genomic integrity to carcinogenesis. Cell Cycle Oct 1;9(19):3904-12. (Epub in ahead of print). PMID: 20935501
- Fujita T., Liu W., Doihara H. and Wan Y. (2009) In vivo dissection of Cdh1/APC in breast carcinogenesis. Int J Cancer. 125(4): 826-36. PMID: 19350629
- Fujita T., Epperly M.W., Zou H., Gollin S.M., Greenberger J.S., and Wan Y. (2008) Regulation of the Anaphase promoting complex-separase cascade by transforming growth factor-beta modulates mitotic progression in bone marrow stromal cells. Mol Biol Cell. 19: 5446-5455 PMID:18843049
- Fujita T. Doihara H., Liu W. and Wan Y. (2008) Dissection of the APCCdh1-Skp2 cascade in breast cancer. Clin Cancer Res 14 (7): 1966-1975 PMID:18381934
- Liu W., Fujita T., Li W., Yang Q., and Wan Y. ( 2008) Proteolysis of CDH1 enhances susceptibility to UV radiation induced apoptosis. Carcinogenesis 29 (2): 263-72. PMID:18174259
- Fujita T. Liu W., Hiroyoshi D. and Wan Y.. (2008) Regulation of Skp2-p27 axis by the Cdh1/anaphase promoting complex pathway in colorectal tumorigenesis. Am J. Pathol. Vol 173, No.1, 217-28. PMID:18535175
- Liu W., Wu G., Lobur D., Li W., and Wan Y. (2007) Cdh1-APC targets Skp2 for destruction in TGF-beta Induced growth inhibition. Mol Cell Biol. Vol.27 (8):2967-79 PMID: 17283060
- Wu G., Glickstein S., Liu W, Fujita T., Li W., Yang Q., Duvoisin R., and Wan Y. (2007) The APC coordinates the initiation of lens differentiation. . Mol Biol Cell. Vol 18 (3):1018-29. PMID:17215516
- Li W., Wu G., and Wan Y. (2007) The dual effects of Cdh1 in myogenesis. FASEB J. 21(13): 3606-17. PMID:17601983
- Wei W*, Ayad NG*, Wan Y, Zhang GJ, Kirschner MW, Kaelin WG Jr. 2004. Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex. Nature 428:194-8. PMID:15014503
- Macdonald M., Wan Y., Wang W., Roberts B., Cheung T., Erickson R., Kirschner M. W. and Liu X. 2004. Cdc34 is required for cell cycle dependent degradation of c-Ski proto-oncoprotein. Oncogene 23(33): 5643-53 PMID:15122324
- Knuesel MP, Wan Y., Xia Z, Holinger EP, Lowe N, Wang W, Liu X. 2003. Identification of novel protein-protein interactions using a versatile mammalian TAP expression system. Mol Cell Proteomics (11): 1225-33 PMID:12963786
- Wan Y., Liu X. and Kirschner W. M. 2001. The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction. Molecular Cell 8(5): 1027-1039. PMID:11741538
- Wan Y. and Kirschner W. M. 2001. Identification of multiple CDH1 homologues in vertebrates conferring different substrate specificities. Proc. Natl. Acad. Sci. USA 98: 13066-13071. PMID:11687641
- Jiang Y., Ma W., Wan Y., Kozasa T., Hassatli T., and Huang X-Y. 1998. G12 directly stimulates a tyrosine kinase and a Ras-Gap through conserved PH-BM domain. Nature 395: 808-813. PMID:9796816
- Wan Y. and Huang X-Y. 1998. Analysis of the Gs/mitogen-activated protein kinase pathway in mutant S49 cells. J. Biol. Chem. 273: 14533-14537. PMID:9603967
- Wan Y., Bence K., Hata A., Kurosaki T. Veillette A., and Huang X-Y. 1997. Genetic evidence for a tyrosine kinase cascade preceding the mitogen-activated protein kinase cascade in vertebrate G-protein signaling. J. Biol. Chem. 272: 17209-17215. PMID:9202044
- Wan Y., Kurosaki T., and Huang X-Y. 1996. Tyrosine kinases in activation of the MAP kinase cascade by G-protein-couple receptors. Nature 380: 541-544. PMID:8606776
- Langhans-Rajasekaran S., Wan Y., and Huang X-Y. 1995. Activation of Tsk and Btk tyrosine kinases by G protein beta-gamma subunits. Proc. Natl. Acad. Sci. USA . 92: 8601-8605. PMID:7567982