Physical Molecular Biology Section
Department of Cell Biology & Physiology
The University of Pittsburgh, School of Medicine
The University of Pittsburgh

Experimental SFM Image of a Glutaraldehyde-fixed Chromatin Fiber.

A glutaraldehyde-fixed chromatin fiber deposited on mica in 5 mM TEA-HCl, pH 7.0. The measured height of the nucleosomes is around 3 nm, which determines the degree of flattening for the model fiber in B.

Yang, G., Leuba, S. H., Bustamante, C., Zlatanova, J. and van Holde, K. Role of linker histones in extended chromatin fibre structure. Nat Struct Biol. 1(11) 761-763 1994

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