Peer-reviewed research articles

Tóth JT, Gulyás G, Tóth DJ, Balla A, Hammond GRV, Hunyady L, et al. (2016) BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation. BBA - Molecular and Cell Biology of Lipids. 1861, 177–187. PubMed Central PMC4733596. Xie S, Bahl K, Reinecke JB, Hammond GRV, Naslavsky N, Caplan S. (2016) The endocytic recycling compartment maintains cargo segregation acquired upon exit from the sorting endosome. Mol Biol Cell. 27, 108–126. PubMed Central PMC4694750. Hammond GRV, Takasuga S, Sasaki T, Balla T. (2015) The ML1Nx2 Phosphatidylinositol 3,5-Bisphosphate Probe Shows Poor Selectivity in Cells. PLoS ONE. 10, e0139957. PubMed Central PMC4604148. Hammond GR, Machner MP, Balla T. A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi. J Cell Biol. 2014 Apr 14;205(1):113-26. doi: 10.1083/jcb.201312072. Epub 2014 Apr 7. PubMed PMID: 24711504; PubMed Central PMCID: PMC3987136. Lukacs V, Yudin Y, Hammond GR, Sharma E, Fukami K, Rohacs T. Distinctive changes in plasma membrane phosphoinositides underlie differential regulation of TRPV1 in nociceptive neurons. J Neurosci. 2013 Jul 10;33(28):11451-63. doi: 10.1523/JNEUROSCI.5637-12.2013. PubMed PMID: 23843517; PubMed Central PMCID:PMC3724548. Hammond GR, Fischer MJ, Anderson KE, Holdich J, Koteci A, Balla T, Irvine RF. PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity. Science. 2012 Aug 10;337(6095):727-30. doi: 10.1126/science.1222483. Epub 2012 Jun 21. PubMed PMID: 22722250; PubMed Central PMCID: PMC3646512. Kruse M, Hammond GR, Hille B. Regulation of voltage-gated potassium channels by PI(4,5)P2. J Gen Physiol. 2012 Aug;140(2):189-205. doi: 10.1085/jgp.201210806. PubMed PMID: 22851677; PubMed Central PMCID: PMC3409096. Ayling LJ, Briddon SJ, Halls ML, Hammond GR, Vaca L, Pacheco J, Hill SJ, Cooper DM. Adenylyl cyclase AC8 directly controls its micro-environment by recruiting the actin cytoskeleton in a cholesterol-rich milieu. J Cell Sci. 2012 Feb 15;125(Pt 4):869-86. doi: 10.1242/jcs.091090. Epub 2012 Mar 7. PubMed PMID: 22399809; PubMed Central PMCID: PMC3311928. Delint-Ramirez I, Willoughby D, Hammond GV, Ayling LJ, Cooper DM. Palmitoylation targets AKAP79 protein to lipid rafts and promotes its regulation of calcium-sensitive adenylyl cyclase type 8. J Biol Chem. 2011 Sep 23;286(38):32962-75. doi: 10.1074/jbc.M111.243899. Epub 2011 Jul 19. PubMed PMID: 21771783; PubMed Central PMCID: PMC3190942. Lindner M, Leitner MG, Halaszovich CR, Hammond GR, Oliver D. Probing the regulation of TASK potassium channels by PI4,5P₂ with switchable phosphoinositide phosphatases. J Physiol. 2011 Jul 1;589(Pt 13):3149-62. doi: 10.1113/jphysiol.2011.208983. Epub 2011 May 3. PubMed PMID: 21540350; PubMed Central PMCID: PMC3145931. Hammond GR, Schiavo G, Irvine RF. Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2). Biochem J. 2009 Jul 29;422(1):23-35. doi: 10.1042/BJ20090428. PubMed PMID: 19508231; PubMed Central PMCID: PMC2722159. Hammond GR, Sim Y, Lagnado L, Irvine RF. Reversible binding and rapid diffusion of proteins in complex with inositol lipids serves to coordinate free movement with spatial information. J Cell Biol. 2009 Jan 26;184(2):297-308. doi: 10.1083/jcb.200809073. Epub 2009 Jan 19. PubMed PMID: 19153221; PubMed Central PMCID: PMC2654307. Hammond GR, Dove SK, Nicol A, Pinxteren JA, Zicha D, Schiavo G. Elimination of plasma membrane phosphatidylinositol (4,5)-bisphosphate is required for exocytosis from mast cells. J Cell Sci. 2006 May 15;119(Pt 10):2084-94. PubMed PMID: 16687737. Meunier FA, Osborne SL, Hammond GR, Cooke FT, Parker PJ, Domin J, Schiavo G. Phosphatidylinositol 3-kinase C2alpha is essential for ATP-dependent priming of neurosecretory granule exocytosis. Mol Biol Cell. 2005 Oct;16(10):4841-51. Epub 2005 Jul 29. PubMed PMID: 16055506; PubMed Central PMCID: PMC1237087.


Hammond GRV. (2016) Does PtdIns(4,5)P2 concentrate so it can multi-task? Biochem Soc Trans. 44, 228–233. PMID 26862209. Hammond GR, Balla T. Polyphosphoinositide binding domains: Key to inositol lipid biology. iochimica Et Biophysica Acta, 1851, 746–758. PubMed PMID: 25732852. Hammond GR, Balla T. A tail of new lipids. EMBO J. 2014 Oct 1;33(19):2140-1. doi: 10.15252/embj.201489773. Epub 2014 Sep 1. PubMed PMID: 25180229; PubMed Central PMCID: PMC4282502. Hammond GR. Membrane biology: Making light work of lipids. Curr Biol. 2012 Oct 23;22(20):R869-71. doi: 10.1016/j.cub.2012.09.005. PubMed PMID: 23098593. Hammond GR, Schiavo G. Polyphosphoinositol lipids: under-PPInning synaptic function in health and disease. Dev Neurobiol. 2007 Aug;67(9):1232-47. Review. PubMed PMID: 17514716. Hammond G, Thomas CL, Schiavo G. Nuclear phosphoinositides and their functions. Curr Top Microbiol Immunol. 2004;282:177-206. Review. PubMed PMID: 14594218.

Department of Cell Biology