Biogenesis and sorting of proteins and lipids for vesicular-tubular transport from the endoplasmic reticulum.

Maternal-fetal signaling during pregnancy

Defining the intracellular signaling pathways that mediate enteroviruses entry and infection of polarized epithelial and endothelial cells.

Regulation, endocytosis, assembly and degradation of calcium-activated potassium channels involved in endothelial, epithelial and neuronal function.

Cell biology and signaling of insulin secretory granule proteins in diabetes

See webpage for detailed research interest.

Cystic Fibrosis and hypertension research is focused on the properties and regulation of ion channels in epithelial cells, the mechanisms of their trafficking to the apical membrane, and their biogenesis within the protein secretory pathway.

See webpage for detailed research interest.

Cell polarity and genetic manipulation of Drosophilia genome.

Studying nuclear protein DNA interactions using single molecule approaches.

Connexin Gap Junction Protein Trafficking, Role of Gap Junction Protein in Cell Migration, Differentiation, Proliferation and Hormone Response.

Pubertal activation of the primate testis; neurobiological triggers, endocrine determinants and intratesticular mechanisms

See webpage for detailed research interest.

Understanding the neurobiology of food intake, body weight regulation, obesity, diabetes and reproduction

Mechanisms underlying the initiation and maintenance of cardiac arrhythmias; development of genetically encoded Ca2+ and voltage sensitive probes, rescuing the infarcted hearts with cell implants; sex differences in ion channel expression and their related arrhythmia phenotype in the long QT syndrome; high-speed depth-resolved images of electrical activity.

Using structural, molecular, and biochemical approaches, my lab focusses on studying membrane protein structure-function relationships and the biosynthesis of these complex protein machines.

Regulation of membrane transport along the endocytic pathway.

Transcriptional regulation in Sertoli cells

The role of ubiquitin-dependent proteolysis in biological regulation

Dendritic cell function and connectivity in the immune system as studied using high end optical imaging.

Physiology and cell biology of ovarian function.

Mechanisms underlying the causes of obesity and type-2 diabetes.